CU-CPTdos2 was used once the reference TLR2-antagonist
CU-CPTdos2 was used once the reference TLR2-antagonist Physical validation To explore the activity of the synthesized and selected compounds 1 to 6 and 9 to 11 on the TLR2 activity, reporter cells overexpressing hTLR2 were used. 7, 10a, 11 Except for 1, all selected compounds decreased TLR2-mediated NF-?B activation in a primary screen (Figure 3A). […]